Zofia GDANIEC, Ph. D., D.Sc.,
                                       Professor of Chemistry




phone:

(+48-61) 8528503

fax:

(+48-61) 8520532


e-mail: zgdan@ibch.poznan.pl




EDUCATION & POSITIONS:

1977

- M.Sc. in physics, Adam Mickiewicz University, Poznań

1989

- Ph.D., organic chemistry, Adam Mickiewicz University, Poznań (under supervision of Prof. R.W. Adamiak); with award

2001

- habilitation, bioorganic chemistry, Institute of Bioorganic Chemistry, Polish Academy of Sciences, Poznań

2002

- Docent, IBCh PAS



EMPLOYMENT:

1977 - 1979

- Pollena-Lechia Company, Poznań

1979 - 1990

- Department of Chemistry, Adam Mickiewicz University, Poznań

1991 -

- Institute of Bioorganic Chemistry PAS, Poznań



FELLOWSHIPS:

1991 - 1992

- 1 year, CEA (Commissariat a l'Energie Atomique), Department of Cellular Biology and Genetics, CEN, Saclay, France

1996 - 1997

- 1 year, Department of Biochemistry, North Carolina State University, Raleigh, USA

1999

- 4 months, Department of Biochemistry, North Carolina State University, Raleigh, USA

2002

- 6 weeks, National Institute of Chemistry, Lubljana, Slovenia



MAJOR PUBLICATIONS (1997-):

Z. Gdaniec, H. Sierzputowska-Gracz, E. C. Theil, Iron Regulatory Element (IRE) and Internal loop/bulge Structure for Ferritin mRNA Studied by Co(III)hexammine binding, molecular modeling and NMR Spectroscopy, Biochemistry, 37, 1505-1512 (1998). [pdf]

W. T. Markiewicz, A. Niewczyk, Z. Gdaniec, D. A. Adamiak, Z. Dauter, W. Rypniewski, M. Chmielewski, Studies on Synthesis and strucutre of O-b-D-Ribofuranosyl(1''-2') Ribonucleosides and Oligonucleotides, Nucleosides & Nucleotides, 17, 411-442 (1998).

A. Burdzy, B. Skalski, S. Paszyc, Z. Gdaniec and R. W. Adamiak, Photosensitized Preparation of Fluorescent Luminarosine and Analogues, Nucleosides and Nucleotides, 17, 143-151 (1998).

E. C. Theil, Y. Ke, Z. Gdaniec, H. Sierzputowska-Gracz, The IRE model for families of RNA structures. Selective recognition by binding proteins (IRPs), NMR spectroscopy and probing with metal coordination complexes, RNA Biochemistry and Biotechnology (eds. J.Barciszewski & B.F.C. Clark) NATO ASI Series, Kluwer Academic Publishers, 241-247 (1999).

A. Fischer, Z. Gdaniec, M. Olejniczak, L. Bielecki, R. W. Adamiak, Does 29-mer RNA hairpin of the HIV-1 TAR RNA sequence bind magnesium? 19F-NMR and modelling studies, Nucleic Acids Symp. Series, 42, 117-118 (1999).

Y. Ke, H. Sierzputowska-Gracz, Z. Gdaniec, E. C. Theil, Internal Loop/Bulge and Hairpin Loop of the Iron- Responsive Element of Ferritin mRNA Contribute to Maximal Iron Regulatory Protein 2 Binding and Translational Regulation in the Iso-iron-responsive Element/Iso-iron Regulatory Protein Family, Biochemistry, 39, 6235-6242 (2000). [pdf]

G. Wenska, B. Skalski, Z. Gdaniec, R. W. Adamiak, J. Matulic-Adamic, L. Beigelman, Photophysical and photochemical properties of C-linked ribosides of pyridin-2-one, J. Photochem. Photobiol. A-Chem., 133, 169-176 (2000).

J. W. Stuart, Z. Gdaniec, R. Guenther, M. Marszalek, E. Sochacka, A. Malkiewicz, P. F. Agris, Functional Anticodon Architecture of Human tRNALys3 Includes Disruption of Intraloop Hydrogen Bonding by the Naturally Occurring Amino Acid Modification, t6A., Biochemistry, 39, 13396-13404 (2000). [pdf]

G. Wenska, K. Taras-Goślińska, K. Lamparska-Kupsik, B. Skalski, M. Gdaniec Z. Gdaniec, Photochemical transformations of 5-halogeno-4-thiouridines, J. Chem. Soc. Perkin Trans. I., 1, 53-57 (2002).

M. Olejniczak, Z. Gdaniec, A. Fischer, T. Grabarkiewicz, Ł. Bielecki and R. W. Adamiak, The bulge region of HIV-1 TAR RNA binds metal ions in solution, Nucleic Acids Res., 30, 4241-4249 (2002). [pdf]

Z. Gdaniec, M. Olejniczak, R. W. Adamiak, Specyficzne wiązanie jonów metali do RNA w roztworze, PAN Działalność naukowa (wybrane zagadnienia), (2003).

S. Hajdasz, Z. Gdaniec, L. Latanowicz, Application of the "model-free approach" to study the intrnal dynamics of biological molecules, Mol. Phys. Rep., 37, 80-87 (2003).

R. W. Adamiak, J. Błażewicz, P. Formanowicz, Z. Gdaniec, M. Kasprzak, M. Popenda and M. Szachniuk, An algorithm for an automatic NOE pathways analysis of 2D NMR spectra of RNA duplexes, J. Comput. Biol., 11 (1), 167-183 (2004).

A. Timoszyk, Z. Gdaniec, L. Latanowicz, The effect of polysialic acid on molecular dynamics of model membranes studied by 31P NMR spectroscopy, Solid State Nucl. Mag., 25, 142-145 (2004). [pdf]

Z. Gdaniec, Spektroskopia NMR w badaniach strukturalnych kwasów nukleinowych. Część I, Wiadomości Chemiczne, 59, 47-65 (2005).

M. Plevnik, Z. Gdaniec, J. Plavec, Solution structure of a modified 2',5'-linked RNA hairpin involved in an equilibrium with duplex, Nucleic Acids Res., 33, 1749-1759 (2005). [Medline]

M. Broda, E. Kierzek, Z. Gdaniec, T. Kuliński, R. Kierzek, Thermodynamic stability of RNA structures formed by CNG trinucleotide repeats. Implication for prediction of RNA structure, Biochemistry, 44, 10873-10882 (2005). [Medline]

V. Balevicius, Z. Gdaniec, H. Fuess, NMR probing of structural peculiarities in ionic solutions close to critical point, J. Chem. Phys., 123, art. no. 224503 (2005). [Medline]

G. Framski, Z. Gdaniec, M. Gdaniec, J. Boryski, A reinvestigated mechanism of ribosylation of adenine under silylating conditions, Tetrahedron, 62, 10123-10129 (2006).

M. Giel-Pietraszuk, Z. Gdaniec, T. Brukwicki, J. Barciszewski, Molecular mechanism of high pressure action on lupanine, J. Mol. Struct., 826, 120-125 (2007).

K.Aidas, A.Marsalka, Z.Gdaniec, V.Balevicius, 13C NMR and DFT study of critical behaviour of binary water/2,6-lutidine solution. Lithuanian Journal of Physics , 47, 443-449, (2007).

Ł. Popenda, R.W. Adamiak, Z. Gdaniec, Bulged Adenosine Influence on the RNA Duplex Conformation in Solution, Biochemistry, 47(18), 5059-5067 (2008). [Medline]

V. Balevicus, Z. Gdaniec, J. Tamuliene, H. Fuess NMR and quantum chemistry study of mesoscopic structuring in 3- methylpyridine/water/NaBr mixture in the vicinity of the phase separation boundary Phase Transitions, 81, 293-301, (2008).

A. Pasternak, R. Kierzek, Z. Gdaniec, M. Gdaniec A locked derivative of 8-aza-7-deazaadenosine Acta Cryst., C64, o467-o470, (2008).

J. Nowak, B. Skalski, Z. Gdaniec, J. Milecki Synthesis of an acyclic nucleoside analog of highly fluorescent luminarosine. Tetrahedron Letters, 50, 1671-1673, (2009).

Ł. Popenda, Ł. Bielecki, Z. Gdaniec, R. W. Adamiak, Structure and dynamics of adenosine bulged RNA duplex reveals formation of the dinucleotide platform in the C:G-A triple, Arkivoc, 3, 130-144 (2009) [pdf].

E.Kierzek, A.Pasternak, K.Pasternak, Z.Gdaniec, I. Yildirim, H.Turner, R.Kierzek Contributions of Stacking, Preorganization, and Hydrogen Bonding to the Thermodynamic Stability of Duplexes between RNA and 2’-O-Methyl RNA with Locked Nucleic Acids. Biochemistry, (2009), 48, 4377-4388

L.Latanowicz, Z.Gdaniec Effect of the frequency of intramolecular motions on the NMR relaxation in liquid state temperature regime Mol. Phys. (2009), 107, 1563-1576

V. Balevicius, Z. Gdaniec, K. Aidas. NMR and DFT study on media effects on proton transfer in hydrogen bonding: concept of molecular probe with an application to ionic and super-polar liquids Phys. Chem. Chem. Phys., (2009), 11, 8592–8600

B. Skalski, K. Taras-Goslińska, Z. Gdaniec, S. Franzen Photoinduced fluorescent crosslinking of 5-chloro- and 5-fluoro-4-thiouridines with thymidine. J. Org. Chem., (2010), 75, 621–626

V. Balevicius, Z. Gdaniec, K. Aidas., J.Tamuliene NMR and Quantum Chemistry Study of Mesoscopic Effects in Ionic Liquids J. Phys. Chem. A, (2010) 114, 5365-5371

A. Olejnik, Z. Gdaniec, E. Kierzek, R. Kierzek The Spontaneous Rearrangement of 2,4-Dinitrophenyl Substituent in Ribonucleosides Under Neutral Conditions Nucleos. Nucleot. Nucl. Acids, (2010) 29, 684-697

G. Wenska, P. Filipiak, K. Taras-Goślińska, A. Sobierajska, Z. Gdaniec Orientation-dependent quenching of the triplet excited 6-thiopurine by nucleobases J. Photochem. Photobiol. A-Chem., (2011) 217, 55–61

L. Latanowicz, Z. Gdaniec Nuclear spin–lattice relaxation and complex motion of macromolecules in solution Mol. Phys., (2011), 109, 853-861

V. Balevicius V, Z. Gdaniec Z, V. Klimavicius, A. Masalka A, J. Plavec J NMR monitoring of nonequilibrium aggregation in ionic solutions Chem. Phys. Lett. (2011) 503,235-238

V. Aleksa, J. Kausteklis, V. Klimavicius, Z. Gdaniec, V. Balevicius Raman and NMR spectroscopy study of liquid crystalline ionogel phase in ionic liquid/H2O mixtures: The state of water. J. Mol. Struct (2011), 993, 91-96




Back to the Adamiak Lab