Back to the Adamiak Lab
               










  • chemical solid-phase synthesis of DNA and RNA fragments

  • sequence-specific introduction of [13C, 15N,]-labelled nucleotide residues to RNA

  • methods of post-synthetic RNA modification including introduction of hypermodified nucleoside residues

  • regiospecific fluorine RNA labelling, 2'-O-MeRNA

  • fluorophore- DNA and RNA labelling

  • design of photochemical probes and their introduction to RNA



  • nucleic chemistry tools

  • RNA/DNA synthesizers (ABI)

  • HPLC (Waters)

  • UV temp. controlled spectrophotometer (Beckman)

  • phosphoimager - aided electrophoresis