Grants from State Committee for Scientific Research (KBN)

• M. D. Bratek-Wiewiórowska
  Crystal engineering of DNA and RNA fragments.
  Aug. 1995 - Jun. 1998
• J. Kapusta
  Regeneration in vitro of selected Lupinus species for genetics and agriculture.
  Sep. 1995 - Feb. 1998
• J. Barciszewski
  Application of the structural studies of proteins to the analysis of their functions.
  Mechanism of plant resistance and properties of plant storage proteins.
  Jan. 1996 - Dec. 1998
• M. Sikorski
  Molecular aspects of plant response to stress and their biotechnological application
  Jan. 1996 - Dec. 1998
• T. Twardowski
  Activity of ribozymes and antisense oligomers in plant translation system.
  Structure-function correlation of nucleic acids.
  Jan. 1996 - Dec. 1998
• R. Kierzek
  The influence of uridine modification on the thermal stability of the RNA duplexes.
  Apr. 1996 - Dec. 1998
• R. Kierzek
  The model ribozymes.
  The structure and self-hydrolytic properties of single-stranded oligoribonucleotides.
  Aug. 1996 - Jul. 1999
• W. J. Krzyżosiak
  Techniques used for detection of dispersed mutations in large genes.
  The BRCA1 gene example.
  Jul. 1996 - Jun. 1999
• W. J. Krzyżosiak
  Structure of human mRNA fragments containing trinucleotide repeats.
  Jul. 1996 - Jun. 1999
• W. J. Krzyżosiak
  Analysis of BRCA1 mRNA structure.
  Jul. 1996 - Jun. 1999
• T. Stępkowski
  The role of the NOD factor from Bradyrhizobium sp. (Lupinus) in determination of morphogenetic processes occuring during nodule development in lupin.
  Jul. 1996 - Jun. 1999
• J. Weres
  Numerical methods for solving inverse problems of heath and mass transport in biological material.
  Jul. 1996 - Jun 1999
• R. W. Adamiak
  TAR element of the retroviral HIV-1 RNA. Chemistry, stereodynamics and interaction with recombinant Tat protein.
  Jan. 1997 - Dec. 1999
• J. Boryski
  Application of transglycosylation method to stereoselective synthesis of biologically active ribonucleosides, 2'deoxy-b-ribonucleosides and their modified analogs.
  Jan. 1997 - Dec. 1999
• J. Ciesiołka
  Ribozymes of hepatitis delta virus.
  Jan. 1997 - Dec. 1999
• M. Figlerowicz
  Structural requirements of genetic recombination in RNA viruses
  Jan. 1997 - Dec. 1999
• W. J. Krzyżosiak
  Technology of genetic test for hereditary predisposition to breast and ovarian cancer
  Jan. 1997 - Dec. 1998
• W. T. Markiewicz
  Development and applications of technologies of dispersed and integra-ted combinatorial oligonucleotide libraries.
  Jul. 1997 - Jun. 2000
• P. Wojtaszek
  Biochemical characterization, ultra-structural localization, and molecular analysis of selected defence-related proteins from white lupin.
  Jul. 1997 - Jun. 2000
• P. Stróżycki
  Molecular basis of iron management in plant tissues.
  Jul. 1997 - Jun. 2000
• J. Podkowiński
  ENOD40 - signal oligopeptide, a new regulator of plant morphogenesis.
  Jul. 1997 - Jun. 2000
• W. J. Krzyżosiak
  Studies on polymorphism of BRCA1 and BRCA2 genes and its association with breast cancer risk.
  Oct. 1997 - Sep. 2000
• A. Kraszewski
  Aryl nucleoside H-phosphonates - novel derivatives of controlled reactivity in oligonucleotide and their analogues synthesis.
  Jan. 1998 - Dec. 2000
• J. Barciszewski
  cDNA cloning, expression and properties of methionyl-tRNA synthetase.
  Jan. 1998 - Dec. 1999
• K. Wojciechowski
  Large scale computer simulations od complex systems
  Jan. 1998 - Dec. 2000
• W. T. Markiewicz
  Chemical synthesis of oligonucleotides carrying 2'-O-ribosyl units.
  Jul. 1998 - Jun. 2000
• W. T. Markiewicz
  Semi-synthetic combinatorial libraries of fragments of antibodies (Fab) and their applications.
  Jan. 1999 - Dec. 2000
• J. Kapusta
  Plant based edible vaccine against Hepatitis B.
  Jan. 1999 - Dec. 2001
• R. W. Adamiak
  Conformational analysis of modified DNA and RNA duplexes by molecular dynamics simulation methods.
  Jan. 1999 - Dec. 2000
• B. Golankiewicz
  Synthesis of second generation tricyclic nucleosides for antiviral and gene anticancer therapy.
  Jan. 1999 - Dec. 2001
• G. Kamieniarz
  Simulations of quantum effects in mesoscopic and low-dimensional magnets and software development.
  Jan. 1999 - Dec. 2001
• J. Węglarz
  New methods and algorithms for resource management in metacomputing environment
  Jan. 1999 - Dec. 2001
• T. Twardowski
  Molecular properties of plant ferritin; correlation between biological functions and potential application
  Apr. 1999 - Dec. 2000
• Z. Gdaniec
  NMR structure and dynamics of 13C-labeled bulged RNA duplexes
  Aug. 1999 - Jul. 2002
• J. Rychlewski
  Structure and dynamics of molecular and atomic systems-study on high accuracy level
  Jan. 2000 - Dec. 2002
• B. Golankiewicz
  Synthesis and biological activity of homo- and heterodimers of acyclovir, ganciclovir and their tricyclic analogues as potential prodrugs and fluorescence carriers
  Jan. 2000 - Dec. 2001
• J. Ciesiołka
  Catalytic cleavage of antigenomic delta ribozyme in the presence of selected divalent metal ions
  Jan. 2000 - Dec. 2001
• W. Krzyżosiak
  Modern RNA technologies in analysis of transcripts of genes undergoing dynamic mutations
  May 2000 - Apr. 2003
• M. Stobiecki
  The role of peroxidases and fenolic secondary metabolites in defense
  March 2000 - Feb. 2002
• M. Figlerowicz
  Studies on the mechanism of genetic RNA recombination in HIV
  Sept. 2000 - Aug. 2003
• M. Alejska
  Influence of homologous RNA recombination on the genetic stability of brome mosaic virus
  Sept. 2000 - Aug. 2003
• R. Kierzek
  Chemical synthesis and thermodynamic property of RNA duplexes and chairpins contained modified adenosines
  Sept. 2000 - Aug. 2002
• T. Kuliński
  The development and application of computational methods for modeling of the structure, dynamics and interactions of RNA motifs
  Aug. 2000 - Jul. 2003
• E. Wyszko
  Molecular mechanism of hybrydogenesis in green frog
  March 2001 - Feb. 2003
• J. Ciesiołka
  Applications of combinatorial oligonucleotide libraries in optimization of the strategy of directed RNA degradation
  March 2001 - Feb. 2004
• R. W. Adamiak
  Structure, properties and conformational equilibria of RNAs at increased, relative to physiological, salt concentration in solution
  Feb. 2001 - Dec. 2003
• J. Barciszewski
  High pressure vaccines against infectious diseases
  March 2001 - Dec. 2003
• A. Cysewska-Sobusiak
  Algorithms for an analysis of linear and 3-dimensional structure of nucleic acids and proteins.
  Jun. 2001 - Dec. 2003
• B. Golankiewicz
  Synthesis of second generation tricyclic nucleosides for antiviral and gene anticancer therapy
  Aug. 2001 - Jan. 2003
• R. W. Adamiak
  The structural aspects and the inhibition of TAR/Tat interaction of retroviruses HIV-1 and HIV-2
  Aug. 2001 - Jul. 2003
• M. Broda
  Studies on the HIV reverse transcriptase ability to copy discontinuous fragments of genomic molecules
  Oct. 2001 - Sept. 2002
• M. Sikorski
  Analysis of the biological function of PR10 class proteins based on gene expression and structural studies using spectroscopic and crystallographic methods
  Nov. 2001 - Oct. 2004
• J. Barciszewski
  Characterization of eukaryotic methionyl-L-tRNA synthetases
  Aug. 2001 - Dec. 2002
• M. Barciszewska
  Structure of ribosomal 5S RNA
  Sept. 2001 - Aug. 2004
• J. Wrzesiński
  Structure of RNA domains that bind Co2+ and Cd2+ ions
  Oct. 2001 - Sept. 2004
• T. Twardowski
  Correlation of structure and function of rRNA domain analysed with strategy of antisense oligonucleotides
  Aug. 2001 - Dec. 2003
• M. Figlerowicz
  RNAi and DNA macroaarays as basic tools in functional genomics of plants of economical importance
  Nov. 2001 - Aug. 2004
• W. Krzyżosiak
  New approaches to molecular diagnostics and therapy of triplet repeat expansion diseases
  Nov. 2001 - Aug. 2004
• W. Krzyżosiak
  Development of sensitive and efficient methods for detecting mutations in human disease genes
  Nov. 2001 - Aug. 2004
• W. Krzyżosiak
  Analysis of cellular pathways leading from dynamic mutations to hereditary neurological diseases
  Nov. 2001 - Aug. 2004
• K. Gulewicz
  Utilization of an embryo model in studies on the prebiotic influence of alpha-galactosides on the organism of chicken
  Mar. 2002 - Feb. 2004
• P. Kwaśnikowski
  Semisynthetic combinatorial libraries of antibodies and their application in obtaining antibodies by in vitro evolution with special respect to antibodies with anti-cancer activity
  Mar. 2002 - Mar. 2005
• M. Sobkowski
  Sources of stereoselctivity during internucleotide bond formation with H-phosphonate method. Studies on methods and potential applications.
  Sept. 2002 - Sept. 2005
  
• M. Figlerowicz
  Role of reverse transcriptase in the generation of unusual genetic variability in HIV.
  Oct. 2002 - Oct. 2004
  
• B. Golankiewicz
  Antiviral and antitumor guanosine analogs contain-ing intrinsic non-radioactive labels.
  Sept. 2002 - Aug. 2005
  
• A. Kraszewski
  Dinucleoside phosphonate-phosphates of nucleoside analogues - a new type of antiviral and anticancer pro-drugs of second generation.
  Sept. 2002 - Aug. 2005
  
• J. Podkowiński
  Isolation of new genes involved in symbiotic nitro-gen fixation and their analysis by means of cDNA arrays.
  Oct. 2002 - Oct. 2005
  
• K. Kulińska
  Development of the universal system architecture of Virtual Laboratory.
  June 2003 - June 2005
  
• W. Rypniewski
  The structure and function of phosphofructokinase from S. cerevisiae and glucosamine-6-phosphate synthase from C. albicans - enzymes of key significance in fungi. Crystallographic analysis.
  Aug. 2003 - Aug. 2006
  
• W. T. Markiewicz
  Polyaminooligonucleotide analogues - synthesis, studies of their antisense, antigene, aptameric proper-ties and applications by combinatorial chemistry approach.
  May 2003 - May 2006
  
• J. Ciesiołka
  Structural characterization of the non-coding regions of hepatitis C viral RNA.
  Mar. 2003 - Mar. 2005
  
• M. Sikorski
  Yellow lupine proteins of PR10.2 subclass.
  Mar. 2003 - Mar. 2005
  
• J. Bujarski
  Identification of recombinationally active regions, present in genomic molecules of brome mosaic virus.
  Nov. 2003 - Feb. 2005
  
• R. Kierzek
  Thermodynamic and structural properties of RNA formed by trinucleotide repeats CNG which are related with many neurological diseases.
  Sept. 2002 - Aug. 2005
  
• A. B. Legocki
  Elaboration and assessment of the experimental edible vaccines against schistosoma (Fasciola hepa-tica) and swine rotaviruses.
  Nov. 2003 - Oct. 2006
  
• M. Figlerowicz
  Complex application of RNAi technology in func-tional genomics and biotechnology of plants.
  Nov. 2003 - Nov. 2006
  
• T. Stępkowski
  The role of lateral gene transfer in evolution of sym-biotic regions in the genus Bradyrhizobium: the evolution of host-range specificity towards lupins and serradella.
  Apr. 2004 - Apr. 2007
  
• W. J. Krzyżosiak
  Application of RNAi and the other antisense strate-gies for allele-specific suppression of mutant genes involved in human hereditary neurological diseases.
  May 2004 - May 2007
  
• M. Chmielewski
  New thermolabile protecting groups - synthesis and applications.
  Aug 2004 - Aug 2007
  
• R. W. Adamiak
  The TAR region of HIV-2 RNA leader and its inter-action with Tat-2 and cyclin T1 proteins.
  Apr. 2004 - Apr. 2006
  
• M. Sikorski
  Structural studies of PR10 proteins in the context oftheir role in plant hormone binding.
  Sept. 2004 - Mar. 2006
  
• M. Stobiecki
  Application of liquid chromatography for monitoring activity of lupine cell wall peroxidases.
  Sept. 2004 - Mar. 2006
  
• J. Barciszewski
  Search and analysis of small nucleolar RNAs (snoRNA) class H/ACA in human genome.
  Nov. 2004 - Nov. 2005
  
• E. Wyszko
  Inhibition of gp41 protein of the Human Immunode-ficiency Virus (HIV-1) using catalytic RNAs and RNA interference.
  Nov. 2004 - Nov. 2007
  
• M. Z. Naskręt-Barciszewska
  A Simple epigenetic method for the diagnosis and classification of brain tumours.
  Nov. 2004 - Nov. 2007
  

Grants within 4th and 5th Framework Program

• T. Twardowski
  Biotechnology and the European public.
  01.06.1996-31.12.1998
• W.T. Markiewicz
  Synthetic oligonucleotide libraries and their application for chemoselection of biomolecules and their analogues.
  01.02.1995-21.06.2000
• T. Twardowski
  AGRO-BIOTECH dissemination and transfer.
• Prof. A.B. Legocki
  Nitrogen fixation in the forage crop alfalfa
  01.02.1994-31.01.1997
• K. Gulewicz
  Pan-european scientific network to improve the quality of protein rich grain legume crops in Central and Eastern Europe for animal/human and industrial uses.
  01.08.1993-31.07.1996
• T. Twardowski
  Universally conserved rRNA sequences of the large ribosomal subunit, in particular the alpha-sarcin domain.
  01.02.1994-31.01.1997
• T. Twardowski
  EU Focus Workshops
  Who should communicate with the public and how?
  2002-2004
  

Scholar Grants of The Foundation for Polish Science

• W. J. Krzyżosiak
  Structural basis of RNA-mediated pathogenesis and RNA directed therapy of human diseases.
  June 2000 - June 2003
  
• R. W. Adamiak
  Structure of the HIV-2 RNA leader and its accessi-bility to the RNAi in view of AIDS therapy.
  June 2004 - June 2007
  

Agricultural Agency of State Treasury

• M. Stobiecki
  Relationship between phenolic compounds profiles in carrot cultivars and resistance to the carrot fly (Psila rosae).
  Sept. 2002 - Dec. 2003
  

Commission of European Communities

• T. Twardowski
  European debates on biotechnology: dimensions of public concern.
  Oct. 1998 - Sept. 2000
  
• T. Twardowski
  European Federation of Biotechnology: task group on public perceptions of biotechnology-2.
  Dec. 1998 - Nov. 2000
  
• T. Twardowski
  Life sciences in European society.
  Feb. 2000 - Jan. 2003
  
• J. Węglarz
  Geant network.
  Nov. 2000 - Oct. 2004
  
• J. Węglarz
  European network for advanced computing technology for science.
  Jan. 2001 - Dec. 2004
  
• T. Twardowski
  EU Focus Workshops: Who should communicate with the public and how?
  2002 - 2004
  
• M. Jaskólski
  A doctoral training network in plant development research: from single molecule to whole plant ADOPT.
  Sept. 2004 - Aug. 2007
  
• W. J. Krzyżosiak
  RNA Interference Technology as Human Therapeutic Tool RIGHT.
  Jan. 2005 - Dec. 2008
  

French-Polish Biotechnology Center

• M. Barciszewska,J. Barciszewski,A. B. Legockiand coworkes.
  27 projects on isolation and cloning of methionyl-tRNA synthetase, transcription mechanism of plant polymerase III and characterization of plant genes and their expression during symbiosis.
  Jul. 1997 - May 1999
  

Fogarty International Research Collaboration Award (FIRCA)

• R. Kierzek
  Folding RNA with Modified Oligonucleotides.
  Feb. 1999 - Jan. 2002
  
• R. Kierzek
  Folding RNA with Modified Oligonucleotides.
  Sept. 2002 - Aug. 2005
  

International Centre for Genetic Engineering and Biotechnology

• M. Jaskólski
  Crystallographic studies of pathogenesis-related proteins from lupine.
  Jan. 2001 - Dec. 2003
  
• A. B. Legocki
  RNAi phenomenon in functional genomics of cultivable plants.
  Jan. 2004 - Dec. 2006
  

AJINOMOTO Co., Inc.

• J. Boryski
  Synthetic Research on 2'-Alkyl Purine Nucleoside Analogues.
  Apr. 2004 - Mar. 2005